Use LyciumBarbarum, fruit, sugar and citric acid as raw materials, through the single factor experiment and L9(34) process for producing LyciumBarbarum and fruit compound health beverage was studied by orthogonal test. Test results showed that the fruit juice, enzymatic hydrolysis conditions were: 0.05%, pectinase enzymolysis temperature 45 ℃, hydrolysis time 4H; wolfberry juice clarifying agent was: adding 0.07% chitosan; the best formula of wolfberry juice addition amount is 35%, calcium juice add 30%, 0.18% citric acid, sucrose adding 8% sodium chloride, 0.03%, vitamin C 0.01%, vitamin B1 0.004‰, vitamin B20.003 ‰. The product is given to the nutritionist and athletes after many experiments, and obtain the consistent high praise