Suitable resin was chosen, and static and dynamic adsorption experiments were carried out to investigate the decolorization and deproteinization effects of polysaccharides from Morinda officinalis How. using the decolorization rate, polysaccharide retention rate and deproteinization rate as main indeces. The results showed that optimum conditions were as follows: D941 resin, room temperature, pH value of polysaccharide solution 5.96, flow rate 2 BV/h, dynamic adsorption. Under the optimal technique, the decolorization rate, polysaccharide retention rate and deproteinization rate were 89.87%, 81.08% and 50.75%, respectively. In conclusion, D941 resin had good decolorization effect and certain deproteinization effect.